Case Study 1: Brad is a 45 year man who has been working as a coal cutter in a mine for 25 years. He likes the job because it pays well and the same mine employed his father. Like many of his colleagues, Brad has had problems with a chronic cough. He has avoided his annual checkups for fear that he will be told he has “black lung” or coal worker’s penumoconiosis. The disease causes fibrosis, decreased diffusing capacity, and permanent small airway dilation. In later stages, pulmonary capillaries, alveoli, and airways are destroyed.
1. How can the disease described above create a mismatch between ventilation and perfusion? Use your understanding of alveolar dead space and physiologic shunt to explain your answer.
2. Individuals with chronic obstructive pulmonary disease have more difficulty exhaling than inhaling. Why is this so?
3. In general terms, what mechanisms in lung disease can affect diffusing capacity across alveolar membranes? Use the Fick law to explain your answer.
At least four double-spaced pages utilizing spelling and grammar checks and following APA 6th Edition formate.
It must be well ordered, logical, and unified, as well as originial and insightful. No Plagerism.
All of the topics in the case study must be addressed.
Please cite at least 3 sourcews; journal articles, textbooks or evidenced-based websites to support the content.
ALL SOURCES MUST BE WITHIN 5 YEARS
Do not use .com, Wikipedia, or up-to-date, etc., for sources.
Completed projected needed by Monday by 11:00 am EST, November 14, 2016
Thank you for your time and consideration on this project.