DISCUSS WHY THE DOG CAN BE CONSIDERED A MODEL FOR CANCER IN HUMANS. IN YOUR ANSWER, COMPARE AND CONTRAST ASPECTS OF A CANCER OF YOUR CHOICE IN DOGS AND HUMANS.
What are some of the steps that you, as a manager, could take to overcome these challenges?
May 3, 2021LITR 211 Week 6 Essay 2 Assignment
May 3, 2021DISCUSS WHY THE DOG CAN BE CONSIDERED A MODEL FOR CANCER IN HUMANS. IN YOUR ANSWER, COMPARE AND CONTRAST ASPECTS OF A CANCER OF YOUR CHOICE IN DOGS AND HUMANS.
DISCUSS WHY THE DOG CAN BE CONSIDERED A MODEL FOR CANCER IN HUMANS. IN YOUR ANSWER, COMPARE AND CONTRAST ASPECTS OF A CANCER OF YOUR CHOICE IN DOGS AND HUMANS.
1. Discuss why the dog can be considered a model for cancer in humans. In your answer,
compare and contrast aspects of a cancer of your choice in dogs and humans. Explain
the challenges facing researchers when using the dog as a spontaneous cancer model
for humans. (30 marks)
2. There are many different forms of radiation therapy used in veterinary oncology.
Discuss the following radiation modalities, integrating the type of radiation they
produce, fraction size and dosing schedules, advantages over conventional external
beam radiation therapy and potential disadvantages. Provide one (1) example of a
clinical application in the veterinary literature for each: (30 marks)
a) intensity modulated radiation therapy (IMRT)
b) stereotactic radiation therapy (SRT)
c) plesiotherapy.
Continued over page
Veterinary Oncology Paper 2 Page 3 of 5
© 2016 The Australian and New Zealand College of Veterinary Scientists ABN 00 50 000894 208
3. You are presented with a seven-year-old female neutered Boxer who has had
intermittent episodes of weakness. The owner reports these are becoming more
frequent, and yesterday the dog collapsed completely, but had recovered by the time
the owner took him to their regular veterinary clinic.
Answer all parts of this question:
a) Formulate a list (oncologic and non-oncologic) of differential diagnoses for this
patient. (3 marks)
b) As part of your initial work up, routine blood tests confirmed hypoglycaemia
(serum glucose 2.0mmol/L (ref 4.47.8mmol/L)), so you performed a serum
insulin level, which returned a reading of 70 μU/L (ref <30 μU/L), with a
concurrent serum glucose of 1.8 mmol/L. State the most likely differential
diagnosis. (1 mark)
c) You formulate a diagnostic plan to further investigate this case. Discuss the
merits of different imaging modalities described for the condition you have
identified. (8 marks)
d) Diagnostic imaging did not identify any obvious lesions. Design a treatment plan
for this patient, presuming she is not in an acute hypoglycaemic crisis currently.
Your answer should briefly include the mechanism of action of any medical
therapies prescribed. (14 marks)
e) Briefly compare and contrast this disease in the domestic ferret. (4 marks)
4. Multiple myeloma can result in a number of pathophysiological and paraneoplastic
conditions in the canine and feline patient. For each of these conditions, describe why
these changes occur, the resulting clinical syndrome, and appropriate management of
these clinical effects. Include in your answer an estimate of how frequently each
condition occurs in dogs and cats. (30 marks)
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