Receptor Activity And Receptor Superfamilies

Directions

Address the following in a paper no longer than two double-spaced pages (not including the reference page) and in APA format. Include at least three peer-reviewed, evidence-based references.

1. Explain the differences between the four main actions a drug can have after binding to a receptor. Describe what an agonist, partial agonist, antagonist, and inverse agonist are. List one or two psychiatric medications that are an example of each of these categories.

2. What is a G-protein-linked receptor? What is an ion channel? How do these differ from each other? Give an example of a neurotransmitter and a medication that act on a G-protein receptor and ion channel.

3. Explain how this information influences how you prescribe medications. Give an example of a patient case or scenario where understanding the drug’s action at the receptor would be critically important in safely treating the patient.

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Rubric

G-Protein-Linked Receptors

G-Protein-Linked Receptors
Criteria	Ratings	Pts
This criterion is linked to a Learning OutcomeAgonist-to-Antagonist Spectrum and Medications	10.0 to >8.0 ptsAll information is accurate and shows a deep understanding of the spectrum. Includes 2 medications in each category.8.0 to >6.0 ptsMost information is accurate and shows a strong understanding of the spectrum. Includes 1 or 2 medications in each category.6.0 to >4.0 ptsSome information is accurate and shows a basic understanding of the spectrum. Includes 1 or 2 medications in each category.4.0 to >2.0 ptsMost information is inaccurate and shows little understanding of the spectrum. Includes 0-1 medications in each category.2.0 to >0 ptsInformation is inaccurate and shows no effort in understanding the spectrum. Does not includes medications in each category.	10.0 pts
This criterion is linked to a Learning OutcomeReceptor Superfamilies	10.0 to >8.0 ptsAll information is accurate and shows a deep understanding of the receptor superfamilies.8.0 to >6.0 ptsMost information is accurate and shows a strong understanding the receptor superfamilies.6.0 to >4.0 ptsSome information is accurate and shows a basic understanding of the receptor superfamilies.4.0 to >2.0 ptsMost information is inaccurate and shows little understanding the receptor superfamilies.2.0 to >0 ptsInformation is inaccurate and shows no effort in understanding the receptor superfamilies.	10.0 pts
This criterion is linked to a Learning OutcomeImpact	10.0 to >8.0 ptsAll information is accurate and shows a deep understanding of the impact on prescribing. Includes a well-written, appropriate example.8.0 to >6.0 ptsMost information is accurate and shows a strong understanding of the impact on prescribing. Includes an appropriate example.6.0 to >4.0 ptsSome information is accurate and shows a basic understanding of the impact on prescribing. Includes a poorly written or not fully appropriate example.4.0 to >2.0 ptsMost information is inaccurate and shows little understanding of the impact on prescribing. Does not include an appropriate example.2.0 to >0 ptsInformation is inaccurate and shows no effort in understanding the impact on prescribing. Does not include an appropriate example.	10.0 pts
This criterion is linked to a Learning OutcomeWriting, Composition, Grammar, Spelling, References, and APA Format	10.0 to >8.0 ptsExcellently written and composed. No errors in format, references, spelling, and grammar.8.0 to >6.0 ptsWell written and composed. A few minor errors in format, references, spelling, and/or grammar.6.0 to >4.0 ptsSomewhat well written and composed. Many minor errors in format, references, spelling, and/or grammar.4.0 to >2.0 ptsPoorly written and composed. Major errors in format, references, spelling, and/or grammar, but still understandable.2.0 to >0 ptsVery poorly written and composed. Major errors in format, references, spelling, and/or grammar make it difficult to understand.	10.0 pts
Total Points: 40.0

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